*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KJ4950000
CHEMICAL NAME           : 7,14-Ethanodibenz(a,b)anthracene-15,16-dicarboxylic
                          acid, 7,14-dimethyl-
LAST UPDATED            : 199106
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C24-H20-O4
MOLECULAR WEIGHT        : 372.44
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 7,12-Dimethylbenzanthracene-7,12-endo-alpha,beta-succinic acid
   * 7,14-Dimethyl-7,14-ethanodibenz(a,b)anthracene-15,16-dicarboxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 297 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - pulmonary emboli
REFERENCE :
   85DLAB "Studies on Chemical Carcinogenesis by Diels-Alder Adducts of
   Carcinogenic Aromatic Hydrocarbons," Earhart, Jr., R.H., Ann Arbor, MI,
   Xerox Univ. Microfilms, 1975  Volume(issue)/page/year: -,107,1975
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 247 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - pulmonary emboli
REFERENCE :
   85DLAB "Studies on Chemical Carcinogenesis by Diels-Alder Adducts of
   Carcinogenic Aromatic Hydrocarbons," Earhart, Jr., R.H., Ann Arbor, MI,
   Xerox Univ. Microfilms, 1975  Volume(issue)/page/year: -,107,1975
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 mg/kg/50D-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Skin and Appendages - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   85DLAB "Studies on Chemical Carcinogenesis by Diels-Alder Adducts of
   Carcinogenic Aromatic Hydrocarbons," Earhart, Jr., R.H., Ann Arbor, MI,
   Xerox Univ. Microfilms, 1975  Volume(issue)/page/year: -,-,1975
 
                            *** END OF RECORD ***