*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KJ4660000
CHEMICAL NAME           : 7,14-Ethanodibenz(a,h)anthracene-15,16-dicarboxylic
                          acid, 7,14-dihydro-, sodium salt
CAS REGISTRY NUMBER     : 63041-43-0
LAST UPDATED            : 199410
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C26-H16-O4.2Na
MOLECULAR WEIGHT        : 438.40
WISWESSER LINE NOTATION : L B66 M6 L666/KA& 2AJ A&&&&TTJ WVO A&VO &-NA- 2
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1,2:5,6-Dibenzanthracene-9,10-endo-alpha,beta-succinic acid sodium salt
   * Sodium 1,2:5,6-dibenzanthracene-9,10-endo-alpha,beta-succinate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2304 mg/kg/16W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   JPBAA7 Journal of Pathology and Bacteriology.  (London, UK)  V.1-96,
   1892-1968.  For publisher information, see JPTLAS. Volume(issue)/page/year:
   54,321,1942
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - leukemia
   Musculoskeletal - tumors
REFERENCE :
   AJCAA7 American Journal of Cancer.  (New York, NY)  V.15-40, 1931-40.  For
   publisher information, see CNREA8.  Volume(issue)/page/year: 27,267,1936
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1824 mg/kg/13W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Endocrine - tumors
REFERENCE :
   JPBAA7 Journal of Pathology and Bacteriology.  (London, UK)  V.1-96,
   1892-1968.  For publisher information, see JPTLAS. Volume(issue)/page/year:
   47,501,1938
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 500 ppm
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 142,453,1948
 
                            *** END OF RECORD ***