*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KL8050000
CHEMICAL NAME           : Ethanol,
                          2-(2-(4-(2-methyl-3-phenothiazin-10-ylpropyl)-1-piper
                          azinyl)ethoxy)-, dihydrochloride
CAS REGISTRY NUMBER     : 60539-20-0
LAST UPDATED            : 199012
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C24-H33-N3-O2-S.2Cl-H
MOLECULAR WEIGHT        : 500.58
WISWESSER LINE NOTATION : T C666 BN ISJ B1Y1&1- AT6N DNTJ D2O2Q &GH 2
SYNONYMS/TRADE NAMES :
   * Dixyrazine dihydrochloride
   *   2-(2-(4-(2-Methyl-3-phenothiazin-10-ylpropyl)-1-piperazinyl)ethoxy)ethan
     ol dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,22,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 102 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,22,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,22,1972
 
                            *** END OF RECORD ***