*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KK2300000
CHEMICAL NAME           : Ethanol,
                          2-(2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperaziny
                          l)ethoxy)ethoxy)-, dimaleate
CAS REGISTRY NUMBER     : 56335-21-8
LAST UPDATED            : 199009
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H31-Cl-N2-O3.2C4-H4-O4
MOLECULAR WEIGHT        : 651.17
WISWESSER LINE NOTATION : T6N DNTJ AYR&R DG& D2O2O2Q &QV1U1VQ 2
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   *   2-(2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethoxy)eth
     anol dimaleate
   * Drimyl
   * Etodroxizine dimaleate
   * Etodroxyzine dimaleate
   * Hydrochlorbenzethylamine dimaleate
   * Indunox
   * Noxadron
   * U.C.B. 1414
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 920 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 9,134,1968
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1 gm/kg
SEX/DURATION            : female 8-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 9,134,1968
 
                            *** END OF RECORD ***