*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KI8400000
CHEMICAL NAME : Ethane, tetrachloro-
CAS REGISTRY NUMBER : 25322-20-7
LAST UPDATED : 199710
DATA ITEMS CITED : 12
MOLECULAR FORMULA : C2-H2-Cl4
MOLECULAR WEIGHT : 167.84
WISWESSER LINE NOTATION : GYGYGG
COMPOUND DESCRIPTOR : Agricultural Chemical
Mutagen
Reproductive Effector
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 200 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf
Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:
30,470,1969
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf
Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:
30,470,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3990 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf
Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:
30,470,1969
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 11 mg/m3/30M
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AISFAR Archivio Italiano di Scienze Farmacologiche. (Modena, Italy) V.1-11,
1932-42; Series 2: V.1-3, 1948-50; Series 3: V.1-15, 1951-65. Discontinued.
Volume(issue)/page/year: 15,1,1937
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 500 mg/kg
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other transferases
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf
Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:
35,21,1974
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - mouse
DOSE : 3200 mg/kg
SEX/DURATION : female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
BIRUAA Biologische Rundschau. (VEB Gustav Fischer Verlag, Postfach 176,
Jena DDR-6900, Ger. Dem. Rep.) V.1- 1963- Volume(issue)/page/year:
14,220,1976
** MUTATION DATA **
TYPE OF TEST : Dominant lethal test
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 250 mg/kg/5D (Intermittent)
REFERENCE :
BIRUAA Biologische Rundschau. (VEB Gustav Fischer Verlag, Postfach 176,
Jena DDR-6900, Ger. Dem. Rep.) V.1- 1963- Volume(issue)/page/year:
18,94,1980
TYPE OF TEST : Sex chromosome loss and nondisjunction
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 420 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X7317
No. of Facilities: 3 (estimated)
No. of Industries: 1
No. of Occupations: 8
No. of Employees: 315 (estimated)
No. of Female Employees: 10 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***