*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KD1920970
CHEMICAL NAME           : 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)
                          furan-1,11(2H)-dione, 5,6,9,17,19,21-
                          hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy
                          -8-(N-(1-pyrrolidinyl )formimidoyl)-, 21-acetate
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C42-H55-N3-O12
MOLECULAR WEIGHT        : 794.00
SYNONYMS/TRADE NAMES :
   * Rifamycin AF/apr
   * Rifamycin SV, 3-((1-pyrrolidinylimino)methyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38KLAC "Structure-Activity Relationship among the Semisynthetic
   Antibiotics,"  Perlman, D., ed., New York, Academic Press, 1977
   Volume(issue)/page/year: -,531,1977
 
                            *** END OF RECORD ***