*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KD1920650
CHEMICAL NAME           : 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)
                          furan-1,11(2H)-dione, 5,6,9,17,19,21-
                          hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy
                          -8-(4-methylpiperidin omethyl)-, 21-acetate
CAS REGISTRY NUMBER     : 4075-47-2
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C44-H60-N2-O12
MOLECULAR WEIGHT        : 809.06
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * NCI 144-148
   * Rifamycin SV, 8-(4-methylpiperidinomethyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 680 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMTRAG Chemotherapia.  (Basel, Switzerland)  V.1-12, 1960-67.  For publisher
   information, see CHTHBK.  Volume(issue)/page/year: 12,155,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 188 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMTRAG Chemotherapia.  (Basel, Switzerland)  V.1-12, 1960-67.  For publisher
   information, see CHTHBK.  Volume(issue)/page/year: 12,155,1967
 
                            *** END OF RECORD ***