*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KG8047000
CHEMICAL NAME           : Estr-4-en-3-one, 17-beta-((trimethylsilyl)oxy)-
CAS REGISTRY NUMBER     : 77572-72-6
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H36-O2-Si
MOLECULAR WEIGHT        : 360.67
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Estr-4-en-3-one, 17-methyl-17-((trimethylsilyl)oxy)-, (17-beta)-
   * 17-Methyl-17-beta-((trimethylsilyl)oxy)estr-4-en-3-one
   * 19-Nortestosterone-17-trimethoxysilyl ether
   * Silabolin
   * Silaboline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 20,143,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 953 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 20,143,1986
 
                            *** END OF RECORD ***