*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : KG7734000
CHEMICAL NAME : Estra-1,3,5(10)-trien-3-ol, 17-beta-(methylthio)-
CAS REGISTRY NUMBER : 108619-67-6
BEILSTEIN REFERENCE NO. : 3144758
REFERENCE : 4-06-00-06617 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C19-H26-O-S
MOLECULAR WEIGHT : 302.51
COMPOUND DESCRIPTOR : Reproductive Effector
Hormone
SYNONYMS/TRADE NAMES :
* 17-beta-(Methylthio)estra-1,3,5(10)-trien-3-ol
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE : 7500 ug/kg
SEX/DURATION : female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
1965 Volume(issue)/page/year: -,111,1965
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE : 4 mg/kg
SEX/DURATION : female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
1965 Volume(issue)/page/year: -,111,1965
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rabbit
DOSE : 12500 ng/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
1965 Volume(issue)/page/year: -,111,1965
*** END OF RECORD ***