*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KF4670000
CHEMICAL NAME           : Erythromycin, cyclic 11,12-carbonate
CAS REGISTRY NUMBER     : 55224-05-0
LAST UPDATED            : 199206
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C38-H65-N-O14
MOLECULAR WEIGHT        : 760.04
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Carbonato ciclico de eritromicina A
   * CWE
   * Cykliczny weglan erytromycyny A
   * Davercin
   * Dravercin
   * Eritromicina A carbonato
   * Erythromycin A 11,12-carbonate
   * Erythromycin A cyclic carbonate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 31,241,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4050 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 31,241,1974
 
                            *** END OF RECORD ***