*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KF4590000
CHEMICAL NAME           : Erythromycin, 9-amino-9-deoxo-, stereoisomer
CAS REGISTRY NUMBER     : 26116-56-3
BEILSTEIN REFERENCE NO. : 4241492
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C37-H70-N2-O12
MOLECULAR WEIGHT        : 735.09
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (9S)-9-Amino-9-deoxoerythromycin
   * 9-Amino-9-deoxo-erythromycin, stereoisomer
   * Epierythromycyl-A-amine
   * 9-Epierythromycylamine
   * Erythromycin, 9-amino-9-deoxo-, (9S)-
   * Erythromycylamine
   * 9(S)-Erythromycylamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 13,83,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 13,83,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 57500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 13,83,1978
 
                            *** END OF RECORD ***