*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE7288500
CHEMICAL NAME           : 5-beta-Ergosta-2,24-dien-26-oic acid,
                          5,6-beta-epoxy-4-beta,22,27-trihydroxy-1-oxo-,
                          delta-lactone, (20S,22R)-
CAS REGISTRY NUMBER     : 5119-48-2
BEILSTEIN REFERENCE NO. : 1335150
REFERENCE               : 5-19-06-00604 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C28-H38-O6
MOLECULAR WEIGHT        : 470.66
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * NSC-101088
   * Withaferin A
   * Withaferine A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 54 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 8,154,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 10 mg/L
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)  V.1-    1966-
   Volume(issue)/page/year: 5,244,1970
 
                            *** END OF RECORD ***