*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE6338400
CHEMICAL NAME           : Ergoline-8-ethanamine, 6-methyl-N-(1-methylethyl)-,
                          (8-beta)-, (Z)-2-butenedioate (1:2)
CAS REGISTRY NUMBER     : 59033-44-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H29-N3.2C4-H4-O4
MOLECULAR WEIGHT        : 543.68
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * D-6-Methyl-8-(beta-isopropylaminoethyl)ergoline-I bis(hydrogen maleate)
   * (8-beta)-6-Methyl-N-(1-methylethyl)ergoline-8-ethanamine  
   (Z)-2-butenedioate (1:2)
   * VUFB10726
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 524 ug/kg
SEX/DURATION            : female 5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 41,2765,1976
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 436 ug/kg
SEX/DURATION            : lactating female 5 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Maternal Effects - postpartum
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 41,2765,1976
 
                            *** END OF RECORD ***