*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE4450000
CHEMICAL NAME           : Ergoline-8-beta-carboxamide,
                          9,10-didehydro-1,6-dimethyl-N-ethyl-
CAS REGISTRY NUMBER     : 7240-57-5
BEILSTEIN REFERENCE NO. : 0042666
REFERENCE               : 4-25-00-00969 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H23-N3-O
MOLECULAR WEIGHT        : 309.45
WISWESSER LINE NOTATION : T C6656 1A P GN LN CUTT&&J EVM2 G L
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * 9,10-Didehydro-N-ethyl-1,6-dimethylergoline-8-beta-carboxamide
   * 1-Methyllysergic acid ethylamide
   * D-1-Methyl lysergic acid monoethylamide
   * MLA-74
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 25 ug/kg
TOXIC EFFECTS :
   Behavioral - hallucinations, distorted perceptions
   Behavioral - toxic psychosis
   Vascular - regional or general arteriolar or venous dilation
REFERENCE :
   PSYPAG Psychopharmacologia (Berlin).  (Berlin, Ger.)  V.1-46, 1959-76.  For
   publisher information, see PSCHDL.  Volume(issue)/page/year: 1,20,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 9 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,101,1972
 
                            *** END OF RECORD ***