*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE2275000
CHEMICAL NAME           : Ergoline-8-beta-carboxamide,
                          1-acetyl-9,10-didehydro-N-ethyl-6-methyl-
CAS REGISTRY NUMBER     : 50485-03-5
BEILSTEIN REFERENCE NO. : 0051958
REFERENCE               : 4-25-00-00972 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H23-N3-O2
MOLECULAR WEIGHT        : 337.46
WISWESSER LINE NOTATION : T C6656 1A P GN LN CUTT&&J EVM2 G1 LV1
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * 1-Acetyl-9,10-didehydro-N-ethyl-6-methylergoline-8-beta-carboxamide
   * 1-Acetyllysergic acid ethylamide
   * d-1-Acetyl lysergic acid monoethylamide
   * ALA-10
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 75 ug/kg
TOXIC EFFECTS :
   Brain and Coverings - changes in surface EEG
   Behavioral - hallucinations, distorted perceptions
   Behavioral - changes in psychophysiological tests
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 8,59,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,94,1972
 
                            *** END OF RECORD ***