*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KE1970000
CHEMICAL NAME           : Ergoline-6-carbonitrile, 8-methyl-1-(2-propenyl)-,
                          (8-beta)-
CAS REGISTRY NUMBER     : 98931-07-8
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H21-N3
MOLECULAR WEIGHT        : 291.43
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1-Allyl-6-cyano-6-norfestuclavine
   * (8-beta)-8-Methyl-1-(2-propenyl)ergoline-6-carbonitrile
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 35,1760,1985
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 umol/plate
REFERENCE :
   ANTDEV Anti-Cancer Drugs.  (Rapid Communications of Oxford Ltd., The Old
   Malthous, Paradise St., Oxford OX1 1LD, UK)  V.1-    1990-
   Volume(issue)/page/year: 3,609,1992
 
                            *** END OF RECORD ***