*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KD1550000
CHEMICAL NAME           : 9,4-(Epoxypentadeca(1,11,13)trienimino)-1H-benzofuro(
                          5,4-g)indole-10,26(9H )-dione, 3-acetyl-
                          5,6,16,18,20-pentahydroxy-14-methoxy-1,2,7,9,15,17,19
                          ,21,25-nonamethyl-, 16-acetate
CAS REGISTRY NUMBER     : 21240-38-0
BEILSTEIN REFERENCE NO. : 5402462
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C43-H54-N2-O12
MOLECULAR WEIGHT        : 790.99
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * NCI 143-462
   * PR 14
   * Rifamycin II, 3'-acetyl-1',2'-dimethyl-
   * Rifamycin PR 14
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38KLAC "Structure-Activity Relationship among the Semisynthetic
   Antibiotics,"  Perlman, D., ed., New York, Academic Press, 1977
   Volume(issue)/page/year: -,531,1977
 
                            *** END OF RECORD ***