*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KD4165600
CHEMICAL NAME           : 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-alp
                          ha-ol, decahydro-3,6,9-trimethyl-, propionate (ester)
CAS REGISTRY NUMBER     : 56973-26-3
LAST UPDATED            : 198509
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H28-O6
MOLECULAR WEIGHT        : 340.46
WISWESSER LINE NOTATION : T6667/DP 3AAF P AXOO EO GOTJ D1 HOV2 I1 M1
SYNONYMS/TRADE NAMES :
   * alpha-Propionyl-dihydroartemether
   * SM 108
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 146 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - food intake (animal)
REFERENCE :
   CYLPDN Zhongguo Yaoli Xuebao.  Acta Pharmacologica Sinica.  Chinese Journal
   of Pharmacology.  (China International Book Trading Corp., POB 2820,
   Beijing, Peop. Rep. China)  V.1-    1980-  Volume(issue)/page/year:
   2,138,1981
 
                            *** END OF RECORD ***