*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KD1146150
CHEMICAL NAME           : 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic
                          acid, 4-(dimethylamino)-3,4,5,6,9,11,12,
                          13,14,16-decahydro-6,13-dimethyl-9,16-dioxo-8-methoxy
                          -3,5,10,11,13-pentahy droxy-, methyl ester,
                          (2-alpha,3-beta,4-alpha,5-beta,6-alpha,11-beta,13-alp
                          ha,14-alpha)-
CAS REGISTRY NUMBER     : 62421-98-1
LAST UPDATED            : 198806
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C30-H33-N-O12
MOLECULAR WEIGHT        : 599.64
WISWESSER LINE NOTATION : T I6 G6 E6 D666 A AO CO FV QVTTT&TTJ JVO1 K1 MQ OQ
                          SO1 V1 WQ A&N1&1 B&Q
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * O-Methyl nogalarol
   * 7-O-Methyl nogalarol
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 850 nmol/L
REFERENCE :
   HXPHAU Handbuch der Experimentellen Pharmakologie.  (Berlin, Ger.)  New
   series: V.1-49, 1935-78. For publisher information, see HEPHD2.
   Volume(issue)/page/year: 38(Pt 2),623,1975
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 850 nmol/L
REFERENCE :
   HXPHAU Handbuch der Experimentellen Pharmakologie.  (Berlin, Ger.)  New
   series: V.1-49, 1935-78. For publisher information, see HEPHD2.
   Volume(issue)/page/year: 38(Pt 2),623,1975
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 12 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   36,1,1981
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 12 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   36,1,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 12 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   36,1,1981
 
                            *** END OF RECORD ***