*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KC9920000
CHEMICAL NAME           : 4,7-Epoxyisoindoline,
                          hexahydro-4-methyl-2-(3-phenothiazin-10-ylpropyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 6593-05-1
LAST UPDATED            : 198509
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H28-N2-O-S.Cl-H
MOLECULAR WEIGHT        : 429.06
WISWESSER LINE NOTATION : T C666 BN ISJ B3- ET C555 A AO ENTJ B1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Hexahydro-4-methyl-2-(3-phenothiazin-10-ylpropyl)-4,7-epoxyisoindoline  
   hydrochloride
   * 10-(3-(4-Methyl-4,7-epoxyhexahydroisoindolin-2-yl)propyl)phenothiazine  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,654,1966
 
                            *** END OF RECORD ***