*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KB4730000
CHEMICAL NAME           : 10H-3,10a-Epidithiopyrazino(1,2-a)indole-1,4-dione,
                          2,3,5a,6-tetrahydro-6-hydroxy-3-
                          (hydroxymethyl)-2-methyl-, monoacetate (ester)
CAS REGISTRY NUMBER     : 29762-25-2
LAST UPDATED            : 198211
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H18-N2-O6-S2
MOLECULAR WEIGHT        : 446.52
WISWESSER LINE NOTATION : T E6 C566 A B 1C O ASSX KNV NNV DH MHJ IOV1 M1Q N1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Gliotoxin monoacetate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 4(1),165,1980
 
                            *** END OF RECORD ***