*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JW4791900
CHEMICAL NAME           : Eburnamenine-14-carboxylic acid,
                          14,15-dihydro-14-hydroxy-, methyl ester,
                          (3-alpha,14-beta,16-alpha)-, compd. with
                          3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-
                          pyridinecarboxaldehyde (1:1)
CAS REGISTRY NUMBER     : 65572-55-6
LAST UPDATED            : 198306
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H26-N2-O3.C8-H10-N-O6-P
MOLECULAR WEIGHT        : 601.65
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Vincamine codecarboxylate
   * Vincamine 5-pyridoxal phosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2721171
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2721171
 
                            *** END OF RECORD ***