*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JW4791850
CHEMICAL NAME           : Eburnamenine-14-carboxylic acid,
                          14,15-dihydro-14-hydroxy-, methyl ester, (3-alpha,14-
                          beta,16-alpha)-, mono(2-(4-hydroxybenzoyl)benzoate)
                          (salt)
CAS REGISTRY NUMBER     : 60683-94-5
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H26-N2-O3.C14-H9-O4
MOLECULAR WEIGHT        : 595.72
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (para-Hydroxy-benzoyl)-2 benzoate de vincamine
   * Vincamine 2-(p-hydroxybenzoyl)benzoate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRXXBL French Demande Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2274283
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRXXBL French Demande Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2274283
 
                            *** END OF RECORD ***