*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JR5775000
CHEMICAL NAME           : Dodecyl alcohol
CAS REGISTRY NUMBER     : 112-53-8
BEILSTEIN REFERENCE NO. : 1738860
REFERENCE               : 4-01-00-01844 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 11
MOLECULAR FORMULA       : C12-H26-O
MOLECULAR WEIGHT        : 186.38
WISWESSER LINE NOTATION : Q12
COMPOUND DESCRIPTOR     : Tumorigen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Alcohol C-12
   * Alfol 12
   * Cachalot L-50
   * Cachalot L-90
   * CO 12
   * CO-1214
   * CO-1214N
   * CO-1214S
   * n-Dodecan-1-ol
   * 1-Dodecanol
   * n-Dodecyl alcohol
   * Dytol J-68
   * EPAL 12
   * Lauric alcohol
   * Laurinic alcohol
   * Lauryl 24
   * Lauryl alcohol
   * n-Lauryl alcohol, primary
   * Lorol 5
   * Lorol 7
   * Lorol 11
   * MA-1214
   * Sipol L12
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human
DOSE/DURATION           : 75 mg/3D (Intermittent)
REACTION SEVERITY       : Severe
REFERENCE :
   85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill,
   V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977
   Volume(issue)/page/year: -,127,1977
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >12800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDZEAK Medizin und Ernaehrung.  (Stuttgart, Fed. Rep. Ger.)  V.1-13,
   1959-72.  Discontinued.  Volume(issue)/page/year: 8,244,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : >10 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 11,95,1973
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19 gm/kg/39W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   9,70,1966

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 10 mg/m3;Skin JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 28510
       No. of Facilities: 1027 (estimated)
       No. of Industries: 28
       No. of Occupations: 40
       No. of Employees: 28625 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 28510
       No. of Facilities: 4159 (estimated)
       No. of Industries: 40
       No. of Occupations: 50
       No. of Employees: 58100 (estimated)
       No. of Female Employees: 20007 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***