*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : IO1440000
CHEMICAL NAME           : 6,9:23,24a-Dimethano-24aH-m-dioxino(4,5,6-st)(4)benza
                          zacycloheneicosine-7, 11,26(10H,16H)- trione,
                          17,18,19,20,21,22,23,24-octahydro-5,16,17,19,20,21,25
                          -heptahydroxy-24-
                          (2-hydroxypropenyl)-23-methoxy-4,8,12,16,18,22,24-hep
                          tamethyl-, 21,24-diacetate
CAS REGISTRY NUMBER     : 23344-16-3
LAST UPDATED            : 198211
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C42-H53-N-O16
MOLECULAR WEIGHT        : 827.96
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * 101-A-2
   * B-44-PC
   * NSC-48810
   * Streptovaricin A
   * Streptovaricinoic acid, 16-hydroxy-, methyl ester, 21-acetate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 375 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 2,475,1980
 
                            *** END OF RECORD ***