*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : IH0770000
CHEMICAL NAME           : Digermoxane, hexabutyl-
CAS REGISTRY NUMBER     : 2587-86-2
BEILSTEIN REFERENCE NO. : 4135565
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C24-H54-Ge2-O
MOLECULAR WEIGHT        : 503.96
SYNONYMS/TRADE NAMES :
   * Bis(tributylgermanium) oxide
   * Bis(tributylgermyl) oxide
   * Germane, oxybis(tributyl-
   * Hexabutyldigermoxane
   * Oxybis(tributylgermane)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   31ZUAV "Investigations in the Field of Organogermanium Chemistry," Rijkens,
   F., and G.J.M. Van Der Kerk, Utrecht, Netherlands, Schotanus & Jens Utrecht
   N.V.,  1964  Volume(issue)/page/year: -,95,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   31ZUAV "Investigations in the Field of Organogermanium Chemistry," Rijkens,
   F., and G.J.M. Van Der Kerk, Utrecht, Netherlands, Schotanus & Jens Utrecht
   N.V.,  1964  Volume(issue)/page/year: -,95,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Musculoskeletal - other changes
REFERENCE :
   31ZUAV "Investigations in the Field of Organogermanium Chemistry," Rijkens,
   F., and G.J.M. Van Der Kerk, Utrecht, Netherlands, Schotanus & Jens Utrecht
   N.V.,  1964  Volume(issue)/page/year: -,95,1964
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   31ZUAV "Investigations in the Field of Organogermanium Chemistry," Rijkens,
   F., and G.J.M. Van Der Kerk, Utrecht, Netherlands, Schotanus & Jens Utrecht
   N.V.,  1964  Volume(issue)/page/year: -,95,1964
 
                            *** END OF RECORD ***