*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JI4870000
CHEMICAL NAME           : 1,3-Dioxolo(4,5-g)isoquinoline,
                          5,6,7,8-tetrahydro-6-methyl-, hydrochloride
CAS REGISTRY NUMBER     : 5985-04-6
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H13-N-O2.Cl-H
MOLECULAR WEIGHT        : 227.71
WISWESSER LINE NOTATION : T C566 DO FO KN EH&&TJ K1 &GH
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Deoxyhydrastinine hydrochloride
   * Hydrohydrastinine, hydrochloride
   * N-Methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline, hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle contraction or spasticity
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 62,165,1938
 
                            *** END OF RECORD ***