*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JI4668000
CHEMICAL NAME           : 1,3-Dioxolo(4,5-g)isoquinoline,
                          5-(alpha-aminoveratryl)-7-methyl-, dihydrochloride
CAS REGISTRY NUMBER     : 17656-51-8
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H20-N2-O4.2Cl-H
MOLECULAR WEIGHT        : 425.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(alpha-Aminoveratryl)-7-methyl-1,3-dioxolo(4,5-g)isoquinoline  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Cardiac - other changes
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,760,1968
 
                            *** END OF RECORD ***