*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JH2796000
CHEMICAL NAME           : 1,3-Dioxa-2-silacyclopentane,
                          4-(chloromethyl)-2,2-dimethyl-
CAS REGISTRY NUMBER     : 73639-62-0
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H11-Cl-O2-Si
MOLECULAR WEIGHT        : 166.70
COMPOUND DESCRIPTOR     : Organometallic
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 4-(Chloromethyl)-2,2-dimethyl-1,3-dioxa-2-silacyclopentane
   * 2,2-Dimethyl-4-(chloromethyl)-1,3-dioxa-2-silacyclopentane
   * SOC
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
REFERENCE :
   CMBID4 Cellular and Molecular Biology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.22-    1977- Volume(issue)/page/year:
   29,299,1983
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 525 mg/kg
SEX/DURATION            : male 21 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   CMBID4 Cellular and Molecular Biology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.22-    1977- Volume(issue)/page/year:
   29,299,1983
 
                            *** END OF RECORD ***