*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JH2715000
CHEMICAL NAME           : 1,3,2-Dioxaphosphorinane,
                          2-(bis(2-chloroethyl)amino)-, 2-oxide
CAS REGISTRY NUMBER     : 63394-91-2
LAST UPDATED            : 198510
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H14-Cl2-N-O3-P
MOLECULAR WEIGHT        : 262.09
WISWESSER LINE NOTATION : T6OPOTJ BO BN2G2G
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * B 525
   * 2-(Bis(2-chloroethyl)amino)-1,3,2-dioxaphosphorinane 2-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,143,1961
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   MGGEAE Molecular and General Genetics.  (Springer-Verlag, Heidelberger Pl.
   3, D-1000 Berlin 33, Fed. Rep. Ger.)  V.99-    1967-
   Volume(issue)/page/year: 102,50,1968
 
                            *** END OF RECORD ***