*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JG8245000
CHEMICAL NAME           : m-Dioxane,
                          5-equatorial-((4,6-bis(1-aziridinyl)-s-triazin-2-yl)a
                          mino)-2,2,5-trimethyl-
CAS REGISTRY NUMBER     : 67026-14-6
BEILSTEIN REFERENCE NO. : 0569934
REFERENCE               : 5-26-09-00231 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H22-N6-O2
MOLECULAR WEIGHT        : 306.42
WISWESSER LINE NOTATION : T6O COTJ B1 B1 E1 EM- BT6N CN ENJ D- AT3NTJ& F-
                          AT3NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5-equatorial-((4,6-Bis(1-aziridinyl)-s-triazin-2-yl)amino)-2,2,5-trimeth
     yl-m-dioxane
   * 4,6-Diaziridinyl-2-(2,2,5-trimethyl-m-dioxan-5-ylamino)-2-s-triazine
   * 1,3,5-Triazin-2-amine,  
   4,6-bis(1-aziridinyl)-N-(2,2,5-trimethyl-1,3-dioxan-5-yl)-
   * s-Triazine, 4,6-diaziridinyl-2-(2,2,5-trimethyl-m-dioxan-5-ylamino)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6496 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JSONDX Journal of Soviet Oncology.  (New York, NY)  V.1-5, 1980-84.
   Volume(issue)/page/year: 1,239,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 12,481,1978
 
                            *** END OF RECORD ***