*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : JG6717200
CHEMICAL NAME           : 1,4-Dioxa-8-azaspiro(4.5)decane,
                          8-(2,6-diamino-4-pyrimidinyl)-, 1'-oxide
CAS REGISTRY NUMBER     : 83540-25-4
LAST UPDATED            : 198606
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H17-N5-O3
MOLECULAR WEIGHT        : 267.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-(2,6-Diamino-4-pyrimidinyl)-1,4-dioxa-8-azaspiro(4.5)decane 1'-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   121,16,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   121,16,1982
 
                            *** END OF RECORD ***