*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR5576000
CHEMICAL NAME           : Aconitan-15-one,
                          14-(benzoyloxy)-3,13-dihydroxy-4-(methoxymethyl)-20-m
                          ethyl-1,6,16- trimethoxy-,
                          (1-alpha,3-alpha,6-alpha,14-alpha,16-beta)-
CAS REGISTRY NUMBER     : 121707-41-3
BEILSTEIN REFERENCE NO. : 0072327
REFERENCE               : 4-21-00-06793 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C31-H41-N-O9
MOLECULAR WEIGHT        : 571.73
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Pyromesaconitine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 15,180,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >30 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JOETD7 Journal of Ethnopharmacology.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1979-  Volume(issue)/page/year:
   35,159,1991
 
                            *** END OF RECORD ***