*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR5569000
CHEMICAL NAME           : Aconitane-3,8,13,14-tetrol,
                          20-ethyl-4-(methoxymethyl)-1,6,16-trimethoxy-,
                          tetraacetate (ester),
                          (1-alpha,3-alpha,6-alpha,14-alpha,16-beta)-
CAS REGISTRY NUMBER     : 38146-91-7
LAST UPDATED            : 199209
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C33-H49-N-O2
MOLECULAR WEIGHT        : 491.83
SYNONYMS/TRADE NAMES :
   * O-Debenzoylindaconitine triacetate
   * Pseudaconine tetraacetate
   * Tetraacetylpseudaconine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHHPAL Yaoxue Xuebao.  Acta Pharmaceutica Sinica.  Pharmaceutical Journal.
   (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
   China)  V.1-    1953-    Suspended 1966-78.  Volume(issue)/page/year:
   19,641,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 15,180,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 153 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHHPAL Yaoxue Xuebao.  Acta Pharmaceutica Sinica.  Pharmaceutical Journal.
   (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
   China)  V.1-    1953-    Suspended 1966-78.  Volume(issue)/page/year:
   19,641,1984
 
                            *** END OF RECORD ***