*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AN3448000
CHEMICAL NAME           : m-Acetotoluidide,
                          4'-chloro-2-pyrrolidinyl-alpha,alpha,alpha-trifluoro-
                          , hydrochloride
LAST UPDATED            : 197909
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C13-H14-Cl-F3-N2-O.Cl-H
MOLECULAR WEIGHT        : 343.20
WISWESSER LINE NOTATION : T5NTJ A1VMR DG CXFFF &GH
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * C 3073
   * 4'-Chloro-2-pyrrolidinyl-alpha,alpha,alpha-trifluoro-m-acetotoluidide,  
   hydrochloride
   * 4'-Chloro-2-pyrrolidinyl-3'-trifluoromethylacetanilide, hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2%
REACTION SEVERITY       : Severe
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,270,1958
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 174 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,270,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,270,1958
 
                            *** END OF RECORD ***