*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AN3424900
CHEMICAL NAME           : o-Acetotoluidide, 3'-chloro-2-ethylamino-,
                          hydrochloride
CAS REGISTRY NUMBER     : 110335-28-9
LAST UPDATED            : 198806
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H15-Cl-N2-O.Cl-H
MOLECULAR WEIGHT        : 263.19
WISWESSER LINE NOTATION : GR B1 CMVM2 &GH
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * 3'-Chloro-2-ethylamino-o-acetotoluidide hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg
REACTION SEVERITY       : Moderate
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 49,80,1960
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 49,80,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 49,80,1960
 
                            *** END OF RECORD ***