*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AN3342000
CHEMICAL NAME           : o-Acetotoluidide,
                          4'-chloro-2-(2-(diethylamino)ethyl)methylamino-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 77966-43-9
LAST UPDATED            : 199012
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C16-H26-Cl-N3-O.2Cl-H
MOLECULAR WEIGHT        : 384.82
WISWESSER LINE NOTATION : GR C1 DMV1N1&2N2&2 &GH 2
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * C 5401
   * 4'-Chloro-2-(2-(diethylamino)ethyl)methylamino-o-acetotoluidide  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2%
REACTION SEVERITY       : Mild
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,262,1959
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,262,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 9,262,1959
 
                            *** END OF RECORD ***