*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HQ6335000
CHEMICAL NAME           : Dibenz(b,e)thiepin,
                          6,11-dihydro-2,9-dichloro-11-(3-(dimethylamino)-1-pro
                          pyl)-, hydrochloride
CAS REGISTRY NUMBER     : 1162-97-6
LAST UPDATED            : 198706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H21-Cl2-N-S
MOLECULAR WEIGHT        : 366.37
WISWESSER LINE NOTATION : T C676 IS&T&J B3N1&1 EG NG &GH
SYNONYMS/TRADE NAMES :
   *   2,9-Dichloro-6,11-dihydro-11-(3-(dimethylamino)-1-propyl)dibenz(b,e)thie
     pin hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 54 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 15,524,1965
 
                            *** END OF RECORD ***