*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HQ4210000
CHEMICAL NAME           : Dibenz(b,f)oxepine,
                          8-fluoro-10-(1-methyl-4-piperazinyl)-, maleate
CAS REGISTRY NUMBER     : 57342-05-9
OTHER CAS REGISTRY NOS. : 56958-64-6
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H19-F-N2-O.C4-H4-O4
MOLECULAR WEIGHT        : 426.48
WISWESSER LINE NOTATION : T C676 BOJ FF I- AT6N DNTJ D1 &QV1U1VQ -C
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Piperazine, 1-(8-fluoro-10-dibenzo(b,f)oxepinyl)-4-methyl-, maleate
   * Piperazine, 1-(8-fluorodibenz(b,f)oxepin-10-yl)-4-methyl-,  
   (Z)-2-butenedioate (1:1)
   * RMI 61280
   * RMI 61280 maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 646 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,1436,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 191 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,1436,1975
 
                            *** END OF RECORD ***