*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HQ4028200
CHEMICAL NAME           : Dibenz(b,f)(1,4)oxazepine,
                          11-(4-methyl-1-piperazinyl)-2-(methylsulfonyl)-
CAS REGISTRY NUMBER     : 22000-66-4
BEILSTEIN REFERENCE NO. : 0582437
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H21-N3-O3-S
MOLECULAR WEIGHT        : 371.49
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 11-(4-Methyl-1-piperazinyl)-2-(methylsulfonyl)dibenz(b,f)(1,4)oxazepine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 9660 mg/kg
SEX/DURATION            : male 19 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
   Reproductive - Fertility - mating performance (e.g. # sperm positive females
   per # females mated; # copulations per # estrus cycles)
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 15,301,1974
 
                            *** END OF RECORD ***