*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HQ2634070
CHEMICAL NAME           : Dibenzo(c,e)thiepin-5-ethanamine,
                          5,7-dihydro-N,N-dimethyl-, 6,6-dioxide,
                          (Z)-2-butenedioate
LAST UPDATED            : 198812
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H21-N-O2-S.C4-H4-O4
MOLECULAR WEIGHT        : 431.54
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5,7-Dihydro-N,N-dimethyldibenzo(c,e)thiepin-5-ethanamine 6,6-dioxide  
   (Z)-2-butenedioate
   * 5-(2-Dimethylaminoethyl)-5,7-dihydrodibenzo(c,e)thiepin 6,6-dioxide  
   hydrogen maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 498 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 51,2848,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 74400 ug/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 51,2848,1986
 
                            *** END OF RECORD ***