*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : HP4650000
CHEMICAL NAME : 3-Dibenzofuranamine
CAS REGISTRY NUMBER : 4106-66-5
BEILSTEIN REFERENCE NO. : 0135942
REFERENCE : 5-18-10-00063 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C12-H9-N-O
MOLECULAR WEIGHT : 183.22
WISWESSER LINE NOTATION : T B656 HOJ EZ
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* 3-Aminodibenzofuran
* 2-Aminodiphenylenoxyd
* Dibenzofuranylamine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 65,294,1939
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3400 mg/kg/72W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Liver - tumors
REFERENCE :
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75,
1903-71. For publisher information, see JCROD7. Volume(issue)/page/year:
61,45,1956
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 13608 mg/kg/54W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Liver - tumors
REFERENCE :
BECCAN Annual Report--Cancer Research Campaign. (Cancer Research Campaign,
2 Carlton House Terrace, London SW1Y 5AR, UK) V.1- 1924-
Volume(issue)/page/year: 46,271,1968
*** END OF RECORD ***