*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HP1366000
CHEMICAL NAME           : 5H-Dibenzo(a,d)cyclohepten-5-one,
                          10-(4-(3-pyridinylmethyl)-1-piperazinyl)-
CAS REGISTRY NUMBER     : 56973-08-1
LAST UPDATED            : 199106
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H23-N3-O
MOLECULAR WEIGHT        : 369.50
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 10-(4-(3-Pyridinylmethyl)-1-piperazinyl)-5H-dibenzo(a,d)cyclohepten-5-one
   * RMI 61199
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,1261,1975
 
                            *** END OF RECORD ***