*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HO2833000
CHEMICAL NAME           : 5H-Dibenz(b,f)azepine,
                          10-(2-(methylamino)ethyl)-5-methyl-, hydrochloride
CAS REGISTRY NUMBER     : 30490-53-0
LAST UPDATED            : 198606
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H20-N2.Cl-H
MOLECULAR WEIGHT        : 300.86
WISWESSER LINE NOTATION : T C676 BNJ B1 I2M1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Dimethyl-N,5 5H-dibenz(b,f)azepine-10-ethanamine
   * 10-(2-(Methylamino)ethyl)-5-methyl-5H-dibenz(b,f)azepine hydrochloride
   * RU 5031
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,371,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,371,1982
 
                            *** END OF RECORD ***