*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HO2583000
CHEMICAL NAME           : 5H-Dibenz(b,f)azepine,
                          8-(ethylthio)-10-(2-(methylamino)ethyl)-5-methyl-,
                          fumarate
CAS REGISTRY NUMBER     : 52963-28-7
LAST UPDATED            : 199610
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H24-N2-S.C4-H4-O4
MOLECULAR WEIGHT        : 440.60
WISWESSER LINE NOTATION : T C676 BNJ B1 FS2 I2M1 &QV1U1VQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Aethylthio-5-methyl-11-(beta-methylaminoaethyl)-(5H)-dibenzo(b,f)azepin 
    fumarat
   * 5H-Dibenz(b,f)azepine-10-ethanamine, N,5-dimethyl-8-(ethylthio)-,  
   (E)-2-butenedioate (1:1)
   * 8-(Ethylthio)-10-(2-(methylamino)ethyl)-5-methyl-5H-dibenz(b,f)azepine  
   fumarate
   * 2-Ethylthio-5-methyl-11-(beta-methylaminoethyl)-(5H)-dibenzo(b,f)azepine  
   fumarate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,371,1982
 
                            *** END OF RECORD ***