*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HO1005000
CHEMICAL NAME           : 5H-Dibenz(b,f)azepine,
                          10,11-dihydro-2-(1-pyrrolidinylmethyl)-
CAS REGISTRY NUMBER     : 64097-59-2
BEILSTEIN REFERENCE NO. : 0425948
REFERENCE               : 5-22-10-00547 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H22-N2
MOLECULAR WEIGHT        : 278.43
WISWESSER LINE NOTATION : T C676 BN&T&J F1- AT5NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 10,11-Dihydro-2-(1-pyrrolidinylmethyl)-5H-dibenz(b,f)azepine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - excitement
   Behavioral - ataxia
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 12,219,1977
 
                            *** END OF RECORD ***