*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HM3655860
CHEMICAL NAME           : 1H-1,4-Diazepine-7-carboxylic acid,
                          2,3-dihydro-5-(2-hydroxyphenyl)-1-methyl-
CAS REGISTRY NUMBER     : 89221-24-9
BEILSTEIN REFERENCE NO. : 5960633
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C13-H14-N2-O3
MOLECULAR WEIGHT        : 246.29
SYNONYMS/TRADE NAMES :
   * Kwas  
   5-(2-hydroxyfenylo)-N-methylo-2,3-dihydro-1,4-diazepino-7-karbokxylowy
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 42,442,1985
 
                            *** END OF RECORD ***