*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HM2786000
CHEMICAL NAME           : 6,9-Diazaspiro(4.5)decane-7,10-dione, 8-methyl-, (S)-
CAS REGISTRY NUMBER     : 90058-29-0
BEILSTEIN REFERENCE NO. : 5936003
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H14-N2-O2
MOLECULAR WEIGHT        : 182.25
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Alaptide
   * Cyclo(1-amino-1-cyclopentanecarbonyl-L-alanyl)
   * (S)-8-Methyl-6,9-diazaspiro(4.5)decane-7,10-dione
   * 6'(S)-Methyl-2',5'-dioxospiro(cyclopentane-1,3'-piperazine)
   * VUFB-15754
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   15,445,1990
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   15,445,1990
 
                            *** END OF RECORD ***