*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HJ8040000
CHEMICAL NAME           : P,P-Diamidoimidodiphosphoric acid,
                          N''-ethyl-N,N,N',N'-tetramethyl-, diethyl ester
CAS REGISTRY NUMBER     : 59740-64-6
BEILSTEIN REFERENCE NO. : 1714933
REFERENCE               : 4-04-00-00435 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H27-N3-O4-P2
MOLECULAR WEIGHT        : 315.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N''-Ethyl-N,N,N',N'-tetramethyl-P,P-diamidoimidodiphosphoric acid diethyl 
    ester
   * Phosphoramidic acid, (bis(dimethylamino)phosphinyl)ethyl-, diethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 105 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PHTXA6 Pharmacology and Toxicology.  English translation of FATOAO.  (New
   York, NY)  V.20-22, 1957-59.  Discontinued.  Volume(issue)/page/year:
   20,136,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 109 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PHTXA6 Pharmacology and Toxicology.  English translation of FATOAO.  (New
   York, NY)  V.20-22, 1957-59.  Discontinued.  Volume(issue)/page/year:
   20,136,1957
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHTXA6 Pharmacology and Toxicology.  English translation of FATOAO.  (New
   York, NY)  V.20-22, 1957-59.  Discontinued.  Volume(issue)/page/year:
   20,136,1957
 
                            *** END OF RECORD ***