*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : HH9230000
CHEMICAL NAME           : Dextran 1
CAS REGISTRY NUMBER     : 9004-54-0
OTHER CAS REGISTRY NOS. : 9013-80-3
                          86280-85-5
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
COMPOUND DESCRIPTOR     : Tumorigen
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Endocrine - tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Endocrine - tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83342
       No. of Facilities: 86 (estimated)
       No. of Industries: 3
       No. of Occupations: 4
       No. of Employees: 369 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83342
       No. of Facilities: 432 (estimated)
       No. of Industries: 3
       No. of Occupations: 6
       No. of Employees: 7612 (estimated)
       No. of Female Employees: 4671 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***